FTO Antikörper (N-Term)

Produktnummer ABIN6254099

Dieser Maus Monoklonal Antikörper erkennt spezifisch FTO in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Ratte und wurde in 6+ Publikationen erwähnt.

Kurzübersicht für FTO Antikörper (N-Term) (ABIN6254099)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FTO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 5-2H10

Produktdetails anti-FTO Antikörper

Bindungsspezifität: N-Term

Spezifität: Specific for endogenous levels of the ~58 kDa FTO protein.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: bovine, canine, horse, non-human primate, sheep

Produktmerkmale: Our Anti-FTO (Fat mass and obesity related protein) Antibody primary antibody is mouse monoclonal. It detects FTO (Fat mass and obesity related protein) and is protein g purified. It is great for use in ELISA, WB, ICC.

Aufreinigung: Protein G purified culture supernatant.

Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat FTO, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Dilution Range: ICC: 1:100-1:600

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-FTO Antikörper (ABIN6254099)

Mao, Dong, Liu, Guo, Ma, Shen, Qian: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." in: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).

Liu, Zhou, Mao, Ji, Qian: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).

Zhou, Wan, Shu, Mao, Liu, Yuan, Zhang, Hess, Brüning, Qian: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).

Wang, Li, Yue, Wang, Kumar, Wechsler-Reya, Zhang, Ogawa, Kellis, Duester, Zhao: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).

Yu, Chen, Huang, Zhu, Song, Zhu, Park, Ji: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).

Zhou, Wan, Gao, Zhang, Jaffrey, Qian: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).

Details zu FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Andere Bezeichnung: FTO

Hintergrund:

Synonyms: AlkB homolog 9 antibody, ALKBH9 antibody, Alpha-ketoglutarate-dependent dioxygenase FTO antibody, AW743446 antibody, Fat mass and obesity-associated protein antibody, FATSO, MOUSE, HOMOLOG OF antibody, Fto antibody, FTO_HUMAN antibody, GDFD antibody, KIAA1752 antibody, mKIAA1752 antibody, Protein fatso antibody

Description Logic: Our Anti-FTO (Fat mass and obesity related protein) Antibody primary antibody is mouse monoclonal. It detects FTO (Fat mass and obesity related protein) and is protein g purified. It is great for use in ELISA, WB, ICC.

Gene Name Alternatives: FTO

Molekulargewicht: 58 kDa

Gen-ID: 79068

UniProt: Q9C0B1